PMP22 Is Critical for Actin-Mediated Cellular Functions and for Establishing Lipid Rafts
نویسندگان
چکیده
منابع مشابه
PMP22 is critical for actin-mediated cellular functions and for establishing lipid rafts.
Haploinsufficiency of peripheral myelin protein 22 (PMP22) causes hereditary neuropathy with liability to pressure palsies, a peripheral nerve lesion induced by minimal trauma or compression. As PMP22 is localized to cholesterol-enriched membrane domains that are closely linked with the underlying actin network, we asked whether the myelin instability associated with PMP22 deficiency could be m...
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ژورنال
عنوان ژورنال: Journal of Neuroscience
سال: 2014
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.1908-14.2014